Blar i forfatter "Grindstad, Thea Karoline Walstad"

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    • Autofagi og Steroidhormoner i Kreftutvikling - et litteraturstudium 

      Grindstad, Thea Karoline Walstad (Master thesis; Mastergradsoppgave, 2014-06-01)
      Autofagi og steroidhormoner er store temaer innen kreftforskning med mange ubesvarte spørsmål. Bakgrunn for oppgaven er en systematisk gjennomgang av litteratur hvor det undersøkes om steroidhormonaktivert autofagi innen kreftutvikling er sannsynlig. Innledningsvis utdypes det hva steroidhormoner er, deres rolle som signaleringssubstanser og påvirkningen på ulike fysiologiske prosesser. Videre ...

    • Estrogen receptors α and β and aromatase as independent predictors for prostate cancer outcome 

      Grindstad, Thea Karoline Walstad (Master thesis; Mastergradsoppgave, 2016-10-11)
      Androgens are considered important in normal prostate physiology and prostate cancer (PCa) pathogenesis. However, androgen-targeted treatment preventing PCa recurrence is still lacking. This indicates additional mediators contributing to cancer development. We sought to determine the prognostic significance of estrogen receptors, ERα and -β, and the aromatase enzyme in PCa. Tissue microarrays ...

    • The role of steroid hormone receptors in prostate cancer. A study of estrogen- and progesterone receptors in adenocarcinoma of the prostate 

      Grindstad, Thea Karoline Walstad (Doctoral thesis; Doktorgradsavhandling, 2018-06-15)
      Steroid hormones and their receptors are vital for numerous physiological processes in the human body, but also related to the development of several malignancies. One such receptor strongly associated with prostate cancer, is the androgen receptor. Other steroid hormone receptors are also implicated in prostate cancer, their role, however, remains to be defined. Using immunohistochemistry and tissue ...